Journal of Equine Veterinary Science
Volume 30, Issue 7 , Pages 365-370 , July 2010

Acellular Urinary Bladder Matrix in a Collagenase Model of Superficial Digital Flexor Tendonitis in Horses

Results of this project were presented at the 53rd Annual Convention of the American Association of Equine Practitioners in Orlando, Florida on December 3, 2007.

  • Ty W. Wallis, DVM, MS, DACVS

      Affiliations

    • Pinnacle Equine Hospital, Louisville, TN
    • Corresponding Author InformationReprint requests: Ty W. Wallis, DVM, MS, DACVS, Pinnacle Equine Hospital, 1958 Jones Bend Rd., Louisville, TN 37777.
    • ,
  • Gary M. Baxter, VMD, MS, DACVS

      Affiliations

    • Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO
    • ,
  • Natasha M. Werpy, DVM, DACVR

      Affiliations

    • Department of Environmental Health and Radiological Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO
    • Equine Orthopaedic Research Center, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO
    • ,
  • Gary L. Mason, DVM, PhD, DACVP

      Affiliations

    • Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO
    • ,
  • David D. Frisbie, DVM, PhD, DACVS

      Affiliations

    • Equine Orthopaedic Research Center, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO
    • ,
  • Nicolai Jarloev, DVM, PhD

      Affiliations

    • Hoersholm Horseclinic, Fredensborg, Denmark

References 

  1. Dyson SJ. Superficial flexor tendonitis in event horses, show jumpers, and dressage horses. In:  Ross MW,  Dyson SJ editor. Diagnosis and management of lameness in the horse. Philadelphia, PA: WB Saunders; 2003;p. 639–643
  2. Ross MW. Management of superficial digital flexor tendonitis. In:  Ross MW,  Dyson SJ editor. Diagnosis and management of lameness in the horse. Philadelphia, PA: WB Saunders; 2003;p. 625–639
  3. Davis CS, Smith RK. Diagnosis and management of tendon and ligament disorders. In:  Auer JA,  Stick JA editor. Equine surgery. 2nd ed. Philadelphia, PA: Saunders; 2006;p. 1086–1110
  4. Smith RK, Webbon PM. The physiology of normal tendon and ligament. In: Proceedings of the Dubai International Equine Symposium. Dubai, UAE: Neyenesch Printers; 1996;p. 55–81
  5. Smith RK. Pathophysiology of tendon injury. In:  Ross MW,  Dyson SJ editor. Diagnosis and management of lameness in the horse. Philadelphia, PA: Saunders; 2003;p. 616–628
  6. McIlwraith CW. Diseases and problems of tendons, ligaments and tendon sheaths. In:  Stashak TS editors. Adams' lameness in horses. Philadelphia, PA: Lippincott Williams & Wilkins; 2002;p. 459–644
  7. Dahlgren LA. Review of treatment options for equine tendon and ligament injuries: what's new and how do they work. Proc Am Assoc Equine Pract. 2005;51:376–382
  8. Dahlgren LA, Nixon AJ, Brower-Toland BD. Effects of beta-aminopropionitrile on equine tendon metabolism in vitro and on effects of insulin-like growth factor-I on matrix production by equine tenocytes. Am J Vet Res. 2001;62:1557–1562
  9. Foland JW, Trotter GW, Powers BE, Wrigley RH, Smith FW. Effect of sodium hyaluronate in collagenase-induced superficial digital flexor tendinitis in horses. Am J Vet Res. 1992;53:2371–2376
  10. Henninger R. Treatment of superficial digital flexor tendinitis. Vet Clin North Am Equine Pract. 1994;10:409–424
  11. Reef VB, Genovese RL, Davis WM. Initial long-term results of horses with superficial digital flexor tendinitis treated with intralesional β-aminoproprionitrile fumarate. Proc Am Assoc Equine Pract. 1997;43:301–305
  12. Mitchell RD. Treatment of tendon and ligament injuries with UBM powder (ACell-Vet). In: Proceedings of the 14th Annual American College of Veterinary Surgeons Symposium. Chicago, IL; 2004:190–193.
  13. Dahlgren LA, van der Meulen MC, Bertram JE, Starrak GS, Nixon AJ. Insulin-like growth factor-I improves cellular and molecular aspects of healing in a collagenase-induced model of flexor tendinitis. J Orthop Res. 2002;20:910–919
  14. Badylak SF. Extracellular matrix as a scaffold for tissue engineering in veterinary medicine: applications to soft tissue healing. Clin Tech Equine Pract. 2004;3:173–181
  15. Badylak SF, Park K, Peppas N, McCabe G, Yoder M. Marrow-derived cells populate scaffolds composed of xenogeneic extracellular matrix. Exp Hematol. 2001;29:1310–1318
  16. Badylak SF, Record R, Lindberg K, Hodde J, Park K. Small intestinal submucosa: a substrate for in vitro cell growth. J Biomater Sci Polym Ed. 1998;9:863–878
  17. Badylak SF. The extracellular matrix as a scaffold for tissue reconstruction. Semin Cell Dev Biol. 2002;13:377–383
  18. Badylak SF. Xenogeneic extracellular matrix as a scaffold for tissue reconstruction. Transplant Immunol. 2004;12:367–377
  19. Dowling BA, Dart AJ, Hodgson DR, Rose RJ, Walsh WR. The effect of recombinant equine growth hormone on the biomechanical properties of healing superficial digital flexor tendons in horses. Vet Surg. 2002;31:320–324
  20. Ross MW. Movement. In:  Ross MW,  Dyson SJ editor. Diagnosis and management of lameness in the horse. Philadelphia, PA: WB Saunders; 2003;p. 60–73
  21. Reef VB, ed. Musculoskeletal ultrasonography. In: Equine diagnostic ultrasound. Philadelphia, PA: WB Saunders; 1998:39–186.

PII: S0737-0806(10)00229-7

doi: 10.1016/j.jevs.2010.05.009

Journal of Equine Veterinary Science
Volume 30, Issue 7 , Pages 365-370 , July 2010

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