Journal of Equine Veterinary Science
Volume 30, Issue 6 , Pages 305-309 , June 2010

Attempts at Superovulation of Mares With Porcine Follicle Stimulating Hormone and Recombinant Equine Follicle Stimulating Hormone

  • Erika L. Cullingford

      Affiliations

    • Animal Reproduction and Biotechnology Laboratory, Colorado State University, Fort Collins, CO
    • ,
  • Edward L. Squires, MS, PhD

      Affiliations

    • Animal Reproduction and Biotechnology Laboratory, Colorado State University, Fort Collins, CO
    • Gluck Equine Research Center, University of Kentucky, Lexington, KY
    • ,
  • Patrick M. McCue, DVM, PhD

      Affiliations

    • Animal Reproduction and Biotechnology Laboratory, Colorado State University, Fort Collins, CO
    • ,
  • George E. Seidel Jr., MS, PhD

      Affiliations

    • Animal Reproduction and Biotechnology Laboratory, Colorado State University, Fort Collins, CO
    • Corresponding Author InformationReprint requests: George E. Seidel, Animal Reproduction and Biotechnology Laboratory, Colorado State University, Rampart Road, Fort Collins, CO 80523.

References 

  1. Squires EL, McCue PM. Superovulation in mares. Anim Reprod Sci. 2006;99:1–8
  2. Squires EL, Garcia RH, Ginther OJ, Voss JL, Seidel GE. Comparison of equine pituitary extract and follicle stimulating hormone for superovulating mares. Theriogenology. 1986;26:661–670
  3. Dippert KD, Hofferer S, Palmer E, Jasko DJ, Squires EL. Initiation of superovulation in mares 5 or 12 days after ovulation using equine pituitary extract with or without GnRH analogue. Theriogenology. 1992;38:695–710
  4. Squires EL, Seidel GE. Superovulation. In: Collection and transfer of equine embryos. Fort Collins, CO: Animal Reproduction and Biotechnology Laboratory Bulletin No. 8, Colorado State University; 1995;p. 32–38
  5. McCue PM. Superovulation. Vet Clin North Am Equine Pract. 1996;12:2–22
  6. Scoggin CF, Meira C, McCue PM, Carnevale EM, Nett TM, Squires EL. Strategies to improve the ovarian response to equine pituitary extract in cyclic mares. Theriogenology. 2002;58:151–164
  7. McCue PM, LeBlanc MM, Squires EL. eFSH in clinical equine practice. Theriogenology. 2007;68:429–433
  8. Fortune JE, Kimmich TL. Purified pig FSH increases the rate of double ovulation in mares. Equine Vet J. 1983;15(Suppl):95
  9. Sirois J, Kimmich TL, Fortune JE. FSH injections early in the cycle induce double ovulations in mares. Theriogenology. 1992;37:300
  10. Krekeler N, Hollinshead FK, Fortier LA, Volkmann DH. Improved ovulation and embryo recovery rates in mares treated with porcine FSH. Theriogenology. 2006;66:663–687
  11. Ignácio FS, Bergfelt DR, Orlandi C, Montechiesi DF, Wechsler FS, Meira C. Ovarian response to pFSH and embryo recovery following follicular wave emergence induced by follicle ablation in mares. Acta Sci Vet. 2007;35(Suppl 3):1245
  12. Roser JF, Jablonka-Shariff A, Daphna–Iken A, Boime I. Expression and bioactivity of single chain recombinant equine luteinizing hormone (LH) and follicle stimulating hormone (FSH). In: Proceedings of the 15th International Congress Animal Reproduction; 2004:572.
  13. DeLuca CA, McCue PM, Patten ML, Squires EL. Comparison of three doses of reFSH for superovulation of mares. Theriogenology. 2008;70:587–588
  14. Squires EL, Carnevale EM, McCue PM, Bruemmer JB. Embryo technologies in the horse. Theriogenology. 2003;59:151–170
  15. Ignácio FS, Bergfelt DR, Montechiesi DF, Araûjo GHM, Carvalho RL, Meira C. Ovarian response and embryo recovery following ablation-induced follicular wave emergence combined with 50 mg of pFSH in mares. Acta Sci Vet. 2008;36(Suppl 2):504
  16. Niswender KD, Alvarenga MA, McCue PM, Hardy QP, Squires EL. Superovulation in cycling mares using equine follicle stimulating hormone (eFSH). J Equine Vet Sci. 2003;23:497–500
  17. Jennings MW, Boime I, Daphna-Iken D, Jablonka-Shariff A, Conley AJ, Colgin M, et al. The efficacy of recombinant equine follicle stimulating hormone (reFSH) to promote follicular growth in mares using a follicular suppression mode. Anim Reprod Sci. 2009;116:291–307
  18. Verver JMP, McCue PM, Cullingford EL, Squires EL. Comparison of porcine FSH and recombinant equine FSH for superovulation of mares. In: 48th British Equine Veterinary Association Congress handbook of presentations; 2009:165.
  19. McCue PM, Squires EL. Persistent anovulatory follicles in the mare. Theriogenology. 2002;58:541–543
  20. Roser JF, Meyers-Brown G, Bidstrup L, Sibley L, Daphna-Iken D, Jablonka-Shariff A, et al. The embryo-to-ovulation ratio and hormone profiles in superovulated mares treated with recombinant equine FSH. In: Proceedings from the 7th International Symposium on Equine Embryo Transfer; Cambridge, UK; 2008: 62–64.
  21. Ginther OJ, Utt MD, Beg MA, Gastal EL, Gastal MO. Negative effect of estradiol on luteinizing hormone throughout the ovulatory luteinizing hormone surge in mares. Biol Reprod. 2007;77:543–550
  22. Thompson DL, Garza F, St. George RL, Rabb MH, Barry BE, French DD. Relationships among LH, FSH and Prolactin secretion, storage and response to secretagogue and hypothalamic GnRH content in ovariectomized pony mares administered testosterone, dihydrotestosteronne, estradiol, progesterone, dexamethasone or follicular fluid. Domest Anim Endocrinol. 1991;8:189–199
  23. Welsh SA, Denniston DJ, Hudson JJ, Bruemmer JE, McCue PM, Squires EL. Exogenous eFSH, follicle coasting, and hCG as a novel superovulation regimen in mares. J Equine Vet Sci. 2006;26:262–270
  24. Flucker MR, Hooper MW, Yuzpe AA. Withholding gonadotropins (“coasting”) to minimize the risk of ovarian hyperstimulation during superovulation and in vitro fertilization-embryo transfer cycles. Fertil Steril. 1999;71:294–301
  25. Sirard MA, Picard L, Dery M, Coenen K, Blondin P. The time interval between FSH administration and ovarian aspiration influences the development of cattle oocytes. Theriogenology. 1999;51:699–708
  26. Logan NL, McCue PM, Squires EL. How to use equine FSH efficiently to enhance embryo recovery. Proc 52nd Ann Convent Am Assoc Equine Pract. 2006;52:242–244

PII: S0737-0806(10)00208-X

doi: 10.1016/j.jevs.2010.04.006

Journal of Equine Veterinary Science
Volume 30, Issue 6 , Pages 305-309 , June 2010

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