Large Experimental Fistula of the Right Dorsal Colon in Horses

Abstract 

Studies in horses with experimental gastrointestinal fistulas may lead to rapid advancements in equine nutrition, as well as prevention and treatment of diseases such as colic and laminitis. The aim of this study was to devise a technique and a cannula to create a large fistula in the right dorsal colon (RDC). A total of 13 horses with normal gastrointestinal tract were used. After the administration of sedatives and local anesthetics, a segment of the right 16th rib was removed, a circular defect was created in the muscular wall, and the RDC was sutured to the muscular wall. The subcutaneous tissue and skin were closed over the attached RDC in eight horses (closed technique), or removed to expose the serosa of the colon sutured to the abdominal wall in five horses (open technique). A full thickness circular incision was made 2 to 6 weeks later to create a fistula. A cannula (diameter, 5 cm) made of natural rubber or silicon was inserted in the fistula. The open surgical technique was easier to perform and resulted in fewer complications. The cannula made of silicon resulted in less pruritus. One horse had a large colon torsion around the colopexy before fistula creation. One of the 12 fistulated horses had a large colon displacement 43 days after cannula insertion. These observations suggest that pexis of the RDC may predispose the horse to large colon displacement or volvulus. The open technique for the colopexy and the cannula made of silicon can be used for creation of a RDC fistula.

Keywords: Colostomy, Gastroenterology, Surgery, Physiology, Nutrition