Journal of Equine Veterinary Science
Volume 30, Issue 1 , Pages 39-43 , January 2010

Influence of Acute Exercise on Serum Homocysteine in Horse

References 

  1. Medina M, Urdiales J, Amores-Sanchez M. Roles of homocysteine in cell metabolism. Eur J Biochem. 2001;268:3871–3882
  2. Mora S, Cook N, Buring JE, Ridker PM, Lee IM. Physical activity and reduced risk of cardiovascular events: potential mediating mechanisms. Circulation. 2007;116:2110–2118
  3. Zee RYL, Mora S, Cheng S, Erlich HA, Lindpaintner K, Rifai N, et al. Homocysteine, 5,10-methylenetetrahydrofolate reductase 677C > T polymorphism, nutrient intake, and incident cardiovascular disease in 24,968 initially healthy women. Clin Chem. 2007;53:845–851
  4. Steenge GR, Verhoef P, Greenhaff PL. The effect of creatine and resistance training on plasma homocysteine concentration in healthy volunteers. Arch Intern Med. 2001;161:1455–1456
  5. Randeva S, Lewandowski KC, Drzewoski J, Brooke-Wavell K, O'Callaghan C, Czupryniak L, et al. Exercise decreases plasma total homocysteine in overweight young women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2002;87:4496–4501
  6. Dankner R, Cheitrit A, Sela BA. Physical activity and lower homocysteine levels in an elderly population. Med Sci Sports Exerc. 2002;34(Suppl):S122
  7. Gaume V, Mougin F, Figard H, Simon-Rigaud ML, N'Guyen UN, Callier J, et al. Physical training decreases total plasma homocysteine and cysteine in middle-aged subjects. Ann Nutr Met. 2005;49:125–131
  8. Hellgren M, Melander A, Ostgren CJ, Rastam L, Lindblad U. Inverse association between plasma homocysteine, sulphonylurea exposure and physical activity: a community-based sample of type 2 diabetes patients in the skaraborg hypertension and diabetes project. Diabetes Obes Metab. 2005;7:421–429
  9. Husemoen L, Thomsen T, Jorgensen T. Changes in lifestyle and total homocysteine in relation to MTHFR(C677T) genotype: the Inter99 study. Eur J Clin Nutr. 2006;60:614–622
  10. Chrysohoou C, Panagiotakos D, Pitsavos C, Zeimbekis A, Zampelas A, Papademetrio L, et al. The associations between smoking, physical activity, dietary habits and plasma homocysteine levels in cardiovascular disease-free people: the ‘ATTICA’ study. Vasc Med. 2005;9:117–123
  11. Drunat S, Moatti N, Paul JL, Cogny A, Benoit M, Demuth K. Homocysteine-induced decrease in endothelin-1 production is initiated at the extracellular level and involves oxidative products. Eur J Biochem. 2001;269:5287–5294
  12. Al-Awami M, Schillinger M, Maca T, Gschwandtner C, Wagner O, Minar E. Homocysteine levels in patients with Raynaud's phenomenon. Zeitschrift Für Gefässkrankheiten. Vasa. 2002;31:87–90
  13. Berhane Y, Bailey SR, Harris PA, Griffiths MJ, Elliott J. In vitro and vivo studies of homocysteine in equine tissue: implications for the pathophysiology of laminitis. Equine Vet J. 2004;36:279–284
  14. Chiaradia E, Gaiti A, Terracina L, Avellini L. Effect of submaximal exercise on horse homocysteinaemia: possible implications for immune cells. Res Vet Sci. 2005;79:9–14
  15. Avellini L, Chiaradia E, Terracina L, Gaiti A. Effect of physical exercise on thiols in the plasma in the athletic horse: connection with the immune system. Vet Res Commun. 2003;27:201–202
  16. Pfeiffer CM, Huff DL, Gunter EW. Rapid and accurate HPLC assay for plasma total homocysteine and cysteine in a clinical laboratory setting. Clin Chem. 1999;45:290–292
  17. Mcdowell IF, Lang D. Homocysteine and endothelial dysfunction: a link with cardiovascular disease. J Nutr. 2000;130:369–372
  18. Fazio F, Assenza A, Crisafulli G, Piccione G, Caola G. The influence of exercise on the daily rhythm of serum homocysteine in horses. J Physiol Sci. 2006;56:455–458
  19. Morris MS, Jacques PF, Selhub J, Rosenberg IH. Total homocysteine and estrogen status indicators in the Third National Health and Nutrition Examination Survey. Am J Epidemiol. 2000;152:140–148
  20. Ganji V, Kafai MR. Demographic, health, lifestyle, and blood vitamin determinants of serum total homocysteine concentrations in the Third National Health and Nutrition Examination Survey, 1988-1994. Am J Clin Nutr. 2003;72:826–833
  21. Simporè J, Pignatelli S, Meli C, Malaguarnera M, Chillemi R, Musumeci S. Nutritional and racial determinants of the increase in plasma homocysteine levels after methionine loading. Curr Ther Res Clin Exp. 2002;63:459–473
  22. Clayton KM. Training show jumper. In:  Hodgson DR,  Rose RJ editor. The athletic horse. Philadelphia, PA: W.B. Saunders; 1994;p. 429–438
  23. Evans DL. Training Thoroughbred racehorses. In:  Hodgson DR,  Rose RJ editor. The athletic horse. Philadelphia, PA: W.B. Saunders; 1994;p. 393–397
  24. Van Guldener C, Stam F, Stehouwer CD. Homocysteine metabolism in renal failure. Kidney Int Suppl. 2001;7:234–237
  25. Gibala MJ. Regulation of skeletal muscle amino acid metabolism during exercise. Int J Sport Nutr Exerc Metab. 2001;11:87–108
  26. Herrmann M, Schorr H, Obeid R, Scharhag J, Urhausen A, Kindermann W, et al. Homocysteine increases during endurance exercise. Clin Chem Lab Med. 2003;41:1518–1524
  27. Tarnopolsky M. Protein requirements for endurance athletes. Nutrition. 2004;20:662–668
  28. Sotgia S, Carru C, Caria M, Tadolini B, Deiana L, Zinellu A. Acute variations in homocysteine levels are related to creatine changes induced by physical activity. Clin Nutr. 2007;26:444–449
  29. Sen CK, Packer L. Thiol homeostasis and supplements in physical exercise. Am J Clin Nutr. 2007;72:653S–669S
  30. Zinellu A, Sotgia S, Caria MA, Tangianu F, Casu G, Deiana L, et al. Effect of acute exercise on low molecular weight thiols in plasma. Scand J Med Sci Sports. 2007;17:452–456
  31. Kirschvink N, De Morffart B, Farnir F, Pincemail J, Lekeux P. Investigation of blood oxidant/antioxidant markers in healthy competition horses of different breeds. Equine Vet J. 2006;36:239–244
  32. Herrmann M, Wilkinson J, Schorr H, Obeid R, Georg T, Urhausen A, et al. Comparison of the influence of volume oriented training and high intensity interval training on serum homocysteine and its cofactors in young, healthy swimmers. Clin Chem Lab Med. 2003;11:1525–1531
  33. Gelecek N, Teoman N, Ozdirenc M, Pnar L, Akan P, Bediz C, et al. Influences of acute and chronic aerobic exercise on the plasma homocysteine level. Ann Nutr Met. 2007;51:53–58

PII: S0737-0806(09)00689-3

doi: 10.1016/j.jevs.2009.11.003

Journal of Equine Veterinary Science
Volume 30, Issue 1 , Pages 39-43 , January 2010