Journal of Equine Veterinary Science
Volume 29, Issue 3 , Pages 167-171 , March 2009

The Effect of Exercise on Equine Gastric Ulcer Syndrome in the Thoroughbred and Standardbred Athlete

  • James A. Orsini, DVM, ACVS

      Affiliations

    • New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Philadelphia
    • Corresponding Author InformationReprint requests: James A. Orsini, DVM, ACVS, University of Pennsylvania, School of Veterinary Medicine, New Bolton Center, 382 West Street Road, Kennett Square, PA 19348.
    • ,
  • Eileen S. Hackett, DVM, MS, ACVS

      Affiliations

    • Department of Clinical Sciences, College of Veterinary and Biomedical Sciences, Colorado State University, Ft Collins, CO
    • ,
  • Nora Grenager, VMD

      Affiliations

    • Steinbeck Country Equine Clinic

References 

  1. Murray MJ. Gastric ulcers in adult horses. Compendium on Continuing Education for the Practicing Veterinarian. Equine Forum. 1994;16:792–794797
  2. Hammond CJ, Mason DK, Watkins KL. Gastric ulceration in mature Thoroughbred horses. Equine Vet J. 1986;18:284–287
  3. Murray MJ, Schusser GF, Pipers FS, Gross SJ. Factors associated with gastric lesions in Thoroughbred racehorses. Equine Vet J. 1996;28:368–374
  4. Rabuffo TS, Orsini JA, Sullivan E, Engiles J, Norman T, Boston R. Association between age or sex and prevalence of gastric ulceration in Standardbred racehorses in training. J Am Vet Med Assoc. 2002;221:1156–1159
  5. Dionne RM, Vrins AA, Doucet MY. Gastric ulcers in Standardbred racehorses: prevalence, lesion description, and risk factors. J Vet Intern Med. 2003;17:218–222
  6. Murray MJ, Grodinsky C, Anderson CW, Radue PF, Schmidt GR. Gastric ulcers in horses: a comparison of endoscopic findings in horses with and without clinical signs. Equine Vet J. 1989;7(Suppl.):68–72
  7. Bertone JJ. Prevalence of gastric ulcers in elite, heavy use western performance horses, in Proceedings 46th Annu Conv Am Assoc Equine Pract 2000;46:256-259.
  8. McClure SR, Carithers DS, Gross SJ, Murray MJ. Gastric ulcer development in horses in a simulated show or training environment. J Am Vet Med Ass. 2005;227:775–777
  9. Orsini JS, Pipers FS. Endoscopic evaluation of the relationship between training, racing, and gastric ulcers (abstr). Vet Surg. 1997;26:424
  10. Lorenzo-Figueras M, Merritt AM. Effects of exercise on gastric volume and pH in the proximal portion of the stomach of horses. Am J Vet Res. 2002;63:1481–1487
  11. Murray MJ. Gastroduodenal ulceration. In: Current therapy in equine medicine. 4th ed. 1997:191-197.
  12. Lester GD, Smith RL, Robertson ID. Effects of treatment with omeprazole or ranitidine on gastric squamous ulceration in racing Thoroughbreds. J Am Vet Med Assoc. 2005;227:1636–1639
  13. Campbell-Thompson ML, Merritt AM. Effect of ranitidine on gastric acid secretion in young male horses. Am J Vet Res. 1987;48:1511–1515
  14. MacAllister CG, Morgan SJ, Borne AT, Pollet RA. Comparison of adverse effects of phenylbutazone, flunixin meglumine, and ketoprofen in horses. J Am Vet Med Assoc. 1993;202:71–77
  15. Murray MJ, Schusser G. Application of gastric pH-metry in horses: measurement of 24-hour gastric pH in horses fed, fasted, and treated with ranitidine. J Vet Intern Med. 1989;6:133
  16. Smyth GB, Young DW, Hammond LS. Effects of diet and feeding on post-prandial serum gastrin and insulin concentrations in adult horses. Equine Vet J. 1988;7(Suppl.):56–59
  17. Furr MO, Taylor L, Kronfeld D. The effects of exercise training on serum gastrin responses in the horse. Cornell Vet. 1994;84:41–45
  18. Lorenzo-Figueras M, Merritt AM. Effects of exercise on gastric volume and pH in the proximal portion of the stomach of horses. Am J Vet Res. 2002;63:1481–1487
  19. Furr MO, Murray MJ, Ferguson DC. The effects of stress on gastric ulceration, T3, T4, reverse T3 and cortisol in neonatal foals. Equine Vet J. 1992;24:37–40
  20. Murray MJ. Gastric ulceration in horses with colic. In: Proceedings Annual Convention of the American Association of Equine Practitioners. 1988;61–68
  21. Murray MJ. Gastric ulceration in horses: 91 cases (1987 − 1990). J Am Vet Med Assoc. 1992;201:117–120
  22. Chameroy KA, Nadeau JA, Bushmich SL, Dinger JE, Hoagland TA, Saxton AM. Prevalence of non-glandular gastric ulcers in horses involved in a university riding program. J Equine Vet Sci. 2006;26:207–211
  23. Bailey CJ, Reid WJS, Hodgson DR, Rose RJ. Factors associated with time until first race and career duration for Thoroughbred racehorses. Am J Vet Res. 1999;60:1196–1200
  24. Bourke JM. Wastage in Thoroughbreds. In: Proceedings Annual Seminar Equine Branch, New Zealand Veterinary Association. 1995;107–119
  25. Estberg L, Gardner LA, Stover SM, Johnston BJ, Case JT, Ardans A. Cumulative racing-speed exercise distance cluster as a risk factor for fatal musculoskeletal injury in Thoroughbred racehorses in California. Prev Med. 1995;24:253–263
  26. Jeffcott LB, Rossdale PD, Freestone J, Frank CJ, Towers-Clark PF. An assessment of wastage in Thoroughbred racing from conception to 4 years of age. Equine Vet J. 1982;14:185–198
  27. Physick-Sheard PW. Career profile of the Canadian Standardbred: influence of age, gait, and sex upon chances of racing. Can J Vet Res. 1986;50:449–456
  28. Vatistas NJ, Sifferman RL, Holste J, Cox JL, Pinalto G, Schultz KT. Induction and maintenance of gastric ulceration in horses in simulated race training. Equine Vet J. 1997;29:40–44
  29. Vatistas NJ, Snyder JR, Carlson G, Johnson B, Arthur RM, Zhou H, et al. Cross-sectional study of gastric ulcers of the squamous mucosa in thoroughbred racehorses. Equine Vet J. 1999;29(Suppl.):34–39
  30. Furr MO, Murray MJ. Treatment of gastric ulcers in horses with histamine type-2 receptor antagonists. Equine Vet J. 1989;7(Suppl.):77–79
  31. Orsini JA, Haddock M, Stine L, Sullivan EK, Rabuffo TS, Smith G. Odds of moderate or severe gastric ulceration in racehorses receiving antiulcer medications. J Am Vet Med Assoc. 2003;223:336–339
  32. Sanchez LC, Murray MJ, Merrit AM. Effect of omeprazole paste on intragastric pH in clinically normal neonatal foals. Am J Vet Res. 2004;65:1039–1041
  33. Vatistas NJ, Snyder JR. Clinical trial of the use of omeprazole in the healing of gastric ulcers in horses maintained in active race training. In: Proceedings 43rd Annual Meeting of the American Association of Equine Practitioners 1997;388-389.

PII: S0737-0806(09)00025-2

doi: 10.1016/j.jevs.2009.01.006

Journal of Equine Veterinary Science
Volume 29, Issue 3 , Pages 167-171 , March 2009

Article Tools