Journal of Equine Veterinary Science
Volume 29, Issue 2 , Pages 95-99 , February 2009

Use of Mohs Micrographically Controlled Surgery in the Management of Equine Penile Squamous Cell Carcinoma

  • Paul G. Hazen, MD

      Affiliations

    • the Department of Dermatology at Case-Western Reserve University School of Medicine, Cleveland, Ohio
    • Corresponding Author InformationReprint requests: Paul G. Hazen, MD, 26908 Detroit Rd, #103, Westlake, OH 44145.
    • ,
  • Brett Berthold, DVM

      Affiliations

    • Cleveland Equine Clinic, Ravenna, Ohio
    • ,
  • Karen L. Turgeon, MD

      Affiliations

    • the Department of Dermatology at Case-Western Reserve University School of Medicine, Cleveland, Ohio
    • ,
  • Gerard Nuovo, MD

      Affiliations

    • The Department of Pathology and Comprehensive Cancer Center at The Ohio State University School of Medicine, Columbus, Ohio

References 

  1. Mohs FE, Snow SN, Larson PO. Mohs micrographic surgery for penile tumors. Urol Clin North Am. 1992;19:291–304
  2. Mullowney PC. Dermatologic diseases of horses: part IV. Environmental, congenital, and neoplastic diseases. Compend Contin Educ Pract Vet. 1985;7:S22–S33
  3. Cotchin E, Maker-Smith J. Tumours in horses encountered in an abattoir survey. Vet Rec. 1975;97:399
  4. MacFadden KE, Pace LW. Clinical manifestations of squamous cell carcinoma in horses. Compend Contin Educ Pract Vet. 1991;13:669–677
  5. Sundberg JP, Burnstein T, Page EH, Kirkham WW, Robinson FR. Neoplasms of equidae. J Am Vet Med Assoc. 1977;170:150–152
  6. Howarth S, Lucke VM, Pearson H. Squamous cell carcinoma of the equine external genitalia: a review and assessment of penile amputation and urethrostomy as a surgical treatment. Equine Vet J. 1991;23:53–58
  7. Fortier LA, Mac Harg MA. Topical use of 5-flurouracil for treatment of squamous cell carcinoma of the external genitalia of horses: 11 cases (1988–1992). JAVMA. 1994;205:1183–1185
  8. Theon AP, Pascoe JR, Meagher DM. Perioperative intratumoral administration of cisplatin for treatment of cutaneous tumors in Equidae. JAVMA. 1994;205:1170–1175
  9. Miller LS, Modlin RL. Human keratinocyte Toll-like receptors promote distinct immune responses. J Invest Dermatol. 2007;127:262–263
  10. Tillman DK, Carroll MT. Topical imiquimod therapy for basal and squamous cell carcinomas: a clinical experience. Cutis. 2007;79:241–248
  11. Ondo AL, Mings SM, Pestak RM, Shanler SD. Topical combination therapy for cutaneous squamous cell carcinoma in situ with 5-fluorouracil cream and imiquimod cream in patients who have failed topical monotherapy. J Am Acad Dermatol. 2006;55:1092–1094
  12. Adams R, Calderwood-Mays MB, Peyton LC. Excision of cutaneous tumors in the horse using histologic guidance. Vet Surg. 1988;17:241–245
  13. Bernstein JA, Hodgin EC, Holloway HW, Hedlund CS, Storey ES, Hubert JD. Mohs micrographic surgery: a technique for total margin assessment in veterinary cutaneous oncologic surgery. Veterinary and Comparative Oncology. 2006;4:151–160
  14. Martens A, De Moor A, Demeulemeester J, Ducatelle R. Histopathological characteristics of five clinical types of equine sarcoid. Res Vet Sci. 2000;69:295–300

PII: S0737-0806(08)00427-9

doi: 10.1016/j.jevs.2008.12.001

Journal of Equine Veterinary Science
Volume 29, Issue 2 , Pages 95-99 , February 2009

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