Journal of Equine Veterinary Science
Volume 29, Issue 2 , Pages 95-99, February 2009

Use of Mohs Micrographically Controlled Surgery in the Management of Equine Penile Squamous Cell Carcinoma

  • Paul G. Hazen, MD

      Affiliations

    • the Department of Dermatology at Case-Western Reserve University School of Medicine, Cleveland, Ohio
    • Corresponding Author InformationReprint requests: Paul G. Hazen, MD, 26908 Detroit Rd, #103, Westlake, OH 44145.
    • ,
  • Brett Berthold, DVM

      Affiliations

    • Cleveland Equine Clinic, Ravenna, Ohio
    • ,
  • Karen L. Turgeon, MD

      Affiliations

    • the Department of Dermatology at Case-Western Reserve University School of Medicine, Cleveland, Ohio
    • ,
  • Gerard Nuovo, MD

      Affiliations

    • The Department of Pathology and Comprehensive Cancer Center at The Ohio State University School of Medicine, Columbus, Ohio

Abstract 

A 30-year-old palomino Standardbred horse was seen with a persistent penile squamous cell carcinoma. After failure using multiple treatments, surgical removal was successfully carried out under local anesthesia using Mohs micrographically controlled surgery. Subsequent examination of the malignant tissue identified bovine papillomavirus exclusively within the nuclei and cytoplasm of tumor cells. The use of Mohs surgery would appear to be useful as an effective, precisely controlled treatment for managing genital squamous cell carcinoma in equine subjects. The presence of papillomavirus within tumor cells would suggest the possibility of causation by an oncogenic papilloma virus and would indicate that careful monitoring of the surgical site should be performed.

Keywords: Equine, Squamous cell carcinoma, Penile tumor, Mohs micrographic surgery, Papillomavirus

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PII: S0737-0806(08)00427-9

doi:10.1016/j.jevs.2008.12.001

Journal of Equine Veterinary Science
Volume 29, Issue 2 , Pages 95-99, February 2009

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