Journal of Equine Veterinary Science
Volume 29, Issue 1 , Pages 42-46 , January 2009

Pregnancy-Associated Laminitis in Mares

  • Philip J. Johnson

      Affiliations

    • Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO
    • Corresponding Author InformationReprint requests: Philip J. Johnson, Veterinary Medical Teaching Hospital at Clydesdale Hall, College of Veterinary Medicine, University of Missouri, 900 East Campus Drive, Columbia, MO 65211.
    • ,
  • Nat T. Messer IV

      Affiliations

    • Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO
    • ,
  • Seshu K. Ganjam

      Affiliations

    • Department of Biomedical Science, College of Veterinary Medicine, University of Missouri, Columbia, MO
    • ,
  • Charles E. Wiedmeyer

      Affiliations

    • Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO

References 

  1. Alford P, Geller S, Richardson B, Slater M, Honnas C, Foreman J, et al. A multicenter, matched case-control study of risk factors for equine laminitis. Prev Vet Med. 2001;49:209–222
  2. Johnson PJ. The equine metabolic syndrome peripheral Cushing's syndrome. Vet Clin North Am Equine Pract. 2002;18:271–293
  3. Messer NT, Johnson PJ. Evidence-based literature pertaining to thyroid dysfunction and Cushing's syndrome in the horse. Vet Clin North Am Equine Pract. 2007;23:329–364
  4. Donaldson MT, Jorgensen AJ, Beech J. Evaluation of suspected pituitary pars intermedia dysfunction in horses with laminitis. J Am Vet Med Assoc. 2004;224:1123–1127
  5. Dorn CR, Garner HE, Coffman JR, Hahn AW, Tritschler LG. Castration and other factors affecting the risk of equine laminitis. Cornell Vet. 1975;65:57–64
  6. Slater MR, Hood DM, Carter GK. Descriptive epidemiological study of equine laminitis. Equine Vet J. 1995;27:364–367
  7. Polzer J, Slater MR. Age, breed, sex and seasonality as risk factors for equine laminitis. Prev Vet Med. 1997;29:179–184
  8. Stashak TS. Lameness. In:  Stashak TS editors. Adams’ lameness in horses. 4th ed. Philadelphia: Lea and Febiger; 1987;p. 486–499
  9. Rohrbach BW, Green EM, Oliver JW, Schneider JF. Aggregate risk study of exposure to endophyte-infected (Acremonium coenophialum) tall fescue as a risk factor for laminitis in horses. Am J Vet Res. 1995;56:22–26
  10. Bailey SR, Habershon-Butcher JL, Ransom KJ, Elliott J, Menzies-Gow NJ. Hypertension and insulin resistance in a mixed-breed population of ponies predisposed to laminitis. Am J Vet Res. 2008;69:122–129
  11. Asplin KE, Sillence MN, Pollitt CC, McGowan CM. Induction of laminitis by prolonged hyperinsulinaemia in clinically normal ponies. Vet J. 2007;174:530–535
  12. French KR, Pollitt CC. Equine laminitis: glucose deprivation and MMP activation induce dermo-epidermal separation in vitro. Equine Vet J. 2004;36:261–266
  13. Fowder AL, Barnes RJ, Comline RS, Silver M. Pancreatic b-cell function in the fetal foal and mare. J Endocrinol. 1980;87:293–301
  14. Wilsher S, Allen WR. Effects of a Streptococcus equi infection-mediated nutritional insult during mid-gestation in primiparous Thoroughbred fillies. Part 1: Placental and fetal development. Equine Vet J. 2006;38:549–557
  15. Firshman AM, Valberg SJ. Factors affecting clinical assessment of insulin sensitivity in horses. Equine Vet J. 2007;39:567–575
  16. Samuel CS. Relaxin: antifibrotic properties and effects in models of disease. Clin Med Res. 2005;3:241–249
  17. Nambo Y, Nagata S, Oikawa M, Yoshihara T, Tsunoda N, Kohsaka T, et al. High concentrations of immunoreactive inhibin in the plasma of mares and fetal gonads during the second half of pregnancy. Reprod Fertil Dev. 1996;8:1137–1145
  18. Reusens B, Ozanne SE, Remacle C. Fetal determinants of type 2 diabetes. Curr Drug Targets. 2007;8:935–941

 Results of this study were presented as an abstract at the Fourth International Conference on Laminitis and Diseases of the Foot, West Palm Beach, FL.

 Refereed

PII: S0737-0806(08)00396-1

doi: 10.1016/j.jevs.2008.11.009

Journal of Equine Veterinary Science
Volume 29, Issue 1 , Pages 42-46 , January 2009

Article Tools