Journal of Equine Veterinary Science
Volume 28, Issue 11 , Pages 627-634 , November 2008

Hormonal Manipulation of the Mare: A Review

  • Edward L. Squires, PhD

      Affiliations

    • Corresponding Author InformationReprint requests: Edward L. Squires, PhD, Animal Reproduction and Biotechnology Laboratory, Colorado State University, Fort Collins, CO 80523-1683.

References 

  1. Squires EL, Stevens WB, McGlothlin DE, Pickett BW. Effect of an oral progestin on the estrous cycle and fertility of mares. J Anim Sci. 1979;49:729–735
  2. Burns PJ, Thompson DL, Storer WA, Gilley RM. Evaluation of sustained release progestogen formulation in mares. Proceedings 7th International Symposium on Equine Embryo Transfer. 2008;82–83
  3. Harrison LA, Squires EL, Nett TM, McKinnon AO. Use of gonadotropin-releasing hormone for hastening ovulation in transitional mares. J Anim Sci. 1990;68:690–699
  4. Niswender KD, McCue PM, Squires EL. Effect of purified equine follicle-stimulating hormone on follicular development and ovulation in transitional mares. J Equine Vet Sci. 2004;24:37–39
  5. Brendemuehl JP, Cross DL. Influence of the dopamine antagonist domperidone on the vernal transition in seasonally anoestrous mares. J Reprod Fertil (Suppl). 2000;56:185–193
  6. Besogenet B, Hansen BS, Daels PF. Induction of reproductive function in anestrous mares using a dopamine antagonist. Theriogenology. 1997;47:467–480
  7. Kelly KK, Thompson DL, Storer WA, Mitcham PB, Gilley RM, Burns PJ. Estradiol interactions with dopamine antagonist in mares: prolactin secretion and reproductive traits. J Equine Vet Sci. 2006;26:517–528
  8. Burns PJ, Morrow C, Abraham J. Evaluation of Biorelease P4 LA300 in the mare. Proceedings 7th International Symposium on Equine Embryo Transfer. 2008;71–72
  9. Progestins Squires EL. In:  McKinnon AO,  Voss JL editor. Equine reproduction. Philadelphia: Lea & Febiger; 1993;p. 311–318
  10. Storer WA, Thompson DL, Gilley RM, Burns PJ. Evaluation of injectable sustained release progestin formulations for suppression of estrus and ovulation in mares. J Equine Vet Sci. 2009;29:∗∗∗
  11. McCue PM, Gee EK, Magee C, Woods GL, Squires EL. Hormone and other medical therapies in equine embryo transfer recipient mares. Proceedings Society for Theriogenology. 2007;27–35
  12. Wilshire S, Clutton-Brock TH, Allen WR, Morris LHA. Transfer of embryos to estrous recipient mares treated with long-acting progesterone and altrenogest. Proceedings 7th International Symposium on Equine Embryo Transfer. 2008;77–78
  13. Handler J, Schonlieb S, Hoppen H, Aurich C. Influence of reproductive stage at PRID insertion on synchronization of estrus and ovulation in mares. Anim Reprod Sci. 2007;97:382–393
  14. Grimmett JB, Hanlon DW, Duirs GF, Jochle W. A new intra-vaginal progesterone-releasing device (Cue-Mare™) for controlling the estrous cycle in mares. Theriogenology. 2002;58:585–587
  15. Stout TAE, Colenbrander B. Suppressing reproductive activity in mares using GnRH vaccines, antagonists or agonists. Anim Reprod Sci. 2004;82:633–643
  16. Elhay M, Newbold A, Britton A, Turley P, Dowsett K, Walker J. Suppression of behavioural and physiological oestrus in the mare by vaccination against GnRH. Aust Vet J. 2007;85:39–45
  17. Imboden I, Janett F, Burger D, Crowe MA, Hässig M, Thun R. Influence of immunization against GnRH on reproductive cyclicity and estrous behavior in mares. Theriogenology. 2008;66:1866–1875
  18. Douglas RH, Ginther OJ. Effect of prostaglandin F2α on the length of diestrus in mares. Prostaglandins. 1972;2:265–268
  19. Loy RG, Buell JR, Stevenson W, Hamm D. Sources of variation and response intervals after prostaglandin treatment in mares with functional corpora lutea. J Reprod Fertil (Suppl). 1979;27:229–235
  20. Nie GJ, Johnson KE, Wenzel JG, Braden TD. Luteal function in mares following administration of oxytocin, cloprostenol or saline on day 0, 1, or 2 post-ovulation. Theriogenology. 2003;60:1119–1125
  21. Hart PJ, Squires EL, Imel KJ, Nett TM. Seasonal variation in hypothalamic content of gonadotropin-releasing hormone (GnRH), pituitary receptors for GnRH, and pituitary content of luteinizing hormoen and follicle-stimulating hormone in the mare. Biol Reprod. 1984;30:1055–1062
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  23. McCue PM, Hudson JJ, Bruemmer JE, Squires EL. Efficacy of hCG at inducing ovulation: a new look at an old issue. AAEP Proc. 2004;50:510–513
  24. Green JM, Raz T, Epp T, Carley S, Card CE. Relationships between utero-ovarian parameters in the ovulatory response to human chorionic gonadotropin in mares. AAEP Proc. 2007;53:563–567
  25. Veronesi MC, Battocchio M, Faustini M, Gandini M, Cairoli F. Relationship between pharmacological induction of estrus and/or ovulation and twin pregnancies in Thoroughbred mares. Dom Anim Endocrinol. 2003;25:133–140
  26. McCue PM, Farquhar VJ, Carnevale EM, Squires EL. Removal of deslorelin (Ovuplant™™) implants 48 h after administration results in normal interovulatory intervals in mares. Theriogenology. 2002;58:865–870
  27. McCue PM, Magee C, Gee EK. Comparison of compounded deslorelin and hCG for induction of ovulation in mares. J Equine Vet Sci. 2007;27:58–61
  28. Yoon MJ, Boime I, Colgin M, Niswender KD, King SS, Alvarenga M, et al. The efficacy of a single chain recombinant equine luteinizing hormone (reLH) in mares: induction of ovulation, hormone profiles, and inter-ovulatory intervals. Dom Anim Endocrinol. 2007;33:470–479
  29. Niswender KD, Roser JF, Boime I, Colgin M. Induction of ovulation in the mare with recombinant equine luteinizing hormone. AAEP Proc. 2006;52:387–388
  30. Squires EL, McCue PM. Superovulation in mares. Anim Reprod Sci. 2007;99:1–8
  31. McCue PM, Leblanc MM, Squires EL. eFSH in clinical equine practice. Theriogenology. 2007;68:429–433
  32. Niswender KD, Jennings M, Boime I, Colgin M, Roser JF. In vivo activity of recombinant follicle-stimulating hormone in cycling mares. AAEP Proc. 2007;53:561–562
  33. James AN, Vogelsang MM, Forrest DW, Stott GG. Efficacy of short-term administration of altrenogest to postpone ovulation in mares. J Equine Vet Sci. 1998;18:329–331
  34. Bruemmer JE, Coy RC, Olson A, Squires EL. Efficacy of altrenogest administration to postpone ovulation and subsequent fertility in mares. J Equine Vet Sci. 2000;20:450–452
  35. Denniston DJ, Crabb JJ, Bruemmer JE, Squires EL. Effects of a gonadotropin-releasing hormone antagonist and altrenogest on luteinizing hormone concentration and ovulation in the mare. J Equine Vet Sci. 2006;26:95–101

 Refereed

PII: S0737-0806(08)00340-7

doi: 10.1016/j.jevs.2008.10.010

Journal of Equine Veterinary Science
Volume 28, Issue 11 , Pages 627-634 , November 2008

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