Journal of Equine Veterinary Science
Volume 28, Issue 9 , Pages 532-539 , September 2008

Effect of Dose of Cloprostenol on the Interval to Ovulation in the Diestrous Mare: A Retrospective Study

  • John R. Newcombe, BVetMed, MRCVS

      Affiliations

    • Warren House Farm, Barracks Lane, West Midlands, UK
    • ,
  • Wolfgang Jöchle, DVM, Dr Med Vet, Dipl ACT

      Affiliations

    • Manahawkin, NJ
    • ,
  • Juan Cuervo-Arango, LV, MSc, MRCVS

      Affiliations

    • Warren House Farm, Barracks Lane, West Midlands, UK
    • Royal Veterinary College, University of London, North Myms, UK
    • Corresponding Author InformationReprint requests: Juan Cuervo-Arango, LV, MSc, MRCVS, Royal Veterinary College, University of London, Hawkshead Lane, North Myms, Herts. AL9 7TA, UK.

References 

  1. Lauderdale JW, Miller PA. Regulations of reproduction in mares with prostaglandin. Proceedings 21st Annual Convention American Association Equine Practitioners, 1975;21:235–244.
  2. Mocklin CM, Paccamonti DL, Eilts BE, Lyle SK, Wouters EGH, Gentry LR, et al. Effects of post-ovulatory PGF2a or cloprostenol on plasma progesterone concentration in mares. Anim Reprod Sci. 2006;94:220–222
  3. Hafs HD, Louis TM, Stellflug JN, Convey EM, Britt JH. Blood LH after PGF2a in dioestrous and ovariectomised cattle. Prostaglandins. 1975;10:1001–1009
  4. Murdoch WJ, Peterson TA, Van Kirk EA, Vincent DL, Inskeep EK. Interactive roles of progesterone, prostaglandins, and collagenase in the ovulatory mechanism of the ewe. Biol Reprod. 1986;35:1187–1194
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  6. Murdoch WJ, Gottsch ML. Proteolytic mechanisms in the ovulatory folliculo-luteal transformation. Connect Tissue Res. 2003;44:50–57
  7. Srikandakumar A, Downey BR. Induction of ovulation in gilts with cloprostenol. Theriogenology. 1989;32:445–449
  8. Arbeiter K, Arbeiter E. Alfaprostol zur ovulationsausloesung waehrend der rosse (2. Mitteilung) (Alfaprostol for the induction of ovulation during oestrus in the mare.). Dtsch Tieraerztl Wochenschr. 1985;92:87–88
  9. Sirois J, Dore M. The late induction of prostaglandin G/H synthase-2 in equine preovulatory follicles supports its role as a determinant of the ovulatory process. Endocrinoloty. 1997;138:4427–4434
  10. Savage NC, Liptrap RM. Induction of ovulation in cyclic mares by administration of a synthetic prostaglandin, fenprostalene, during oestrus. J Reprod Fert (Suppl). 1987;35:239–243
  11. Lamond DR, Buell JR, Stevenson WS. Efficacy of a prostaglandin analogue in reproduction in the anoestrus mare. Theriogenology. 1975;3:77–85
  12. Howey WP, Jöchle W, Barnes WJ. Evaluation of clinical and luteolytic effects of a novel prostaglandin analogue in normal and problem mares. Aust Vet J. 1983;60:180–183
  13. Reiner UR, Jöchle W. Effectiveness of a novel prostaglandin analogue in postpartum mares and mares with early season anoestrus. Zuchthygiene. 1981;16:110–115
  14. Jöchle W, Irvine CHG, Alexander SL, Newby TJ. Release of LH, FSH and GnRH into pituitary venous blood in mares treated with a PGF analogue, luprostiol, during the transition period. J Reprod Fertil (Suppl). 1987;35:261–267
  15. Ginther OJ. Ultrasonic imaging and reproductive events in the mare. Cross Plains, WI: Equiservices. 1986;
  16. Pierson RA, Ginther OJ. Ultrasonic evaluation of the corpus luteum of the mare. Theriogenology. 1985;23:795–806
  17. Newcombe JR. Ultrasonography of ovulation and development of the corpus luteum in the mare: a personal view. Equine Vet Educ. 1996;8:47–58
  18. Kiefer , Roser JF, Evans JW, Neely DP, Pacheco CA. Progesterone patterns observed with multiple injections of a PGF2a analogue in the cyclic mare. J Reprod Fertil (Suppl). 1979;27:237–244
  19. Noden PA, Oxender WD, Hafs HD. Early changes in serum progesterone, oestradiol and LH during prostaglandin F2 induced luteolysis in mares. J Anim Sci. 1978;47:666–671
  20. Armstrong DT, Gringwich DI, Moon YS, Zamecnik J. Inhibition of ovulation in rabbits by intrafollicular injection of indomethacin and prostaglandin F anti-serum. Life Sci. 1974;14:129–140
  21. Sharma SC, Wilson CMW, Pugh DM. In vitro production of prostaglandins E and F by the guinea pig ovarian tissue. Prostaglandins. 1976;11:555–568
  22. Tam WH, Roy RJJ. A possible role of prostaglandin F2 alpha in the development of ovarian follicles in guinea-pigs. J Reprod Fertil. 1982;66:277–282
  23. Peters MW, Pursley JR, Smith GW. Inhibition of the follicular PGE2 synthesis and ovulation following ultrasound-mediated intrafollicular injection of the selective cyclooxigenase-2 inhibitor NS-398 in cattle. J Anim Sci. 2004;82:1656–1662
  24. Quinglei L, Jimenez-Krassel F, Kobayashi Y, Ireland J, Smith G. Effect of intrafollicular indomethacin injection on gonadotropin surge-induced expression of select extracellular matrix degrading enzymes and their inhibitors in bovine preovulatory follicles. Reproduction. 2006;131:533–543
  25. Ginther OJ, Pierson A. Regular and irregular characteristics of ovulation and the interovulatory interval in mares. J Equine Vet Sci. 1989;9:4–12
  26. Wüstenhagen A, Handler J, Kindahl H, Aurich C. Luteal function and oestrus cycle characteristics in mares treated with subtherapeutic doses of prostaglandin F2a. Theriogenology. 2002;58:537–539
  27. Handler J, Wüstenhagen A, Schams D, Kindahl H, Aurich C. Estrous cycle characteristics, luteal function, secretion of oxytocin (OT) and plasma concentrations of 15-keto-13,14-dihydro-PGF2alpha (PGF2alpha metabolite) after administration of low doses of prostaglandin F2 alpha (PGF2alpha) in pony mares. Theriogenology. 2004;61:1573–1582

 Refereed

PII: S0737-0806(08)00245-1

doi: 10.1016/j.jevs.2008.07.017

Journal of Equine Veterinary Science
Volume 28, Issue 9 , Pages 532-539 , September 2008

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