Journal of Equine Veterinary Science
Volume 28, Issue 7 , Pages 395-401 , July 2008

Adaptation of Equine Locomotor Muscle Fiber Types to Endurance and Intensive High Speed Training

  • K. Leisson

      Affiliations

    • Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences,Tartu, Estonia
    • Corresponding Author InformationReprint requests: K. Leisson, Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.
    • ,
  • Ü. Jaakma

      Affiliations

    • Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences,Tartu, Estonia
    • ,
  • T. Seene

      Affiliations

    • Department of Functional Morphology, University of Tartu, Tartu, Estonia

References 

  1. Rivero JL, Ruz A, Marti-Korff S, Estepa JC, Aguilera-Tejero E, Werkmann J, et al. Effects of intensity and duration of exercise on muscular responses to training of thoroughbred horses. J Appl Physiol. 2007;102:1871–1882
  2. Rivero JL, Ruz A, Marti-Korfft S, Lindner A. Contribution of exercise intensity and duration to training-linked myosin transitions in thoroughbreds. Equine Vet J (Suppl). 2006;36:311–315
  3. Nader GA. Concurrent strength and endurance training: from molecules to man. Med Sci Sports Exerc. 2006;38:1965–1970
  4. Votion DM, Navet R, Lacombe VA, Sluse F, Essen-Gustavsson B, Hinchcliff KW, et al. Muscle energetics in exercising horses. Equine Comp Exerc Physiol. 2007;4:105–118
  5. Pehme A, Seene T. Age-related differences in skeletal muscle: effect of strength training. In:  Vain A editors. Acta Academiae Olympiquae Estoniae Tartu. 13:2005;p. 47–54
  6. Rogers CW, Firth EC, McIlwraith CW, Barneveld A, Goodship AE, Kawcak CE, et al. Evaluation of a new strategy to modulate skeletal development in racehorses by imposing track-based exercise during growth: the effects on 2- and 3-year-old racing careers. Equine Vet J. 2008;40:119–127
  7. Seene T, Umnova M, Kaasik P, Alev K, Pehme A. Overtraining injuries in athletic populations. In:  Tiidus PM editors. Skeletal muscle damage and repair. Champaign, IL: Human Kinetics; 2008;p. 173–184
  8. de Graaf-Roelfsema E, Keizer HA, van Breda E, Wijnberg ID, van der Kolk JH. Hormonal responses to acute exercise, training and overtraining: a review with emphasis on the horse. Vet Q. 2007;29:82–101
  9. Bottinelli R. Functional heterogeneity of mammalian single muscle fibers: do myosin isoforms tell the whole story?. Eur J Physiol. 2001;443:6–17
  10. Palencia P, Quiroz-Rothe E, Rivero JL. New insights into the skeletal muscle phenotype of equine motor neuron disease: a quantitative approach. Acta Neuropathol. 2005;109:272–284
  11. Grotmol S, Totland GK, Kryvi H, Breistol A, Essen-Gustavsson B, Lindholm A. Spatial distribution of fiber types within skeletal muscle fascicles from Standardbred horses. Anat Rec. 2002;268:131–136
  12. Rivero JL, Talmadge RJ, Edgerton VR. Myosin heavy chain isoforms in adult equine skeletal muscle: an immunohistochemical and electrophoretic study. Anat Rec. 1996;246:185–194
  13. Seene T, Alev K, Kaasik P, Pehme A, Parring A-M. Endurance training: volume-dependent adaptational changes in myosin. Int J Sports Med. 2005;26:815–821
  14. Strøm D, Holm S. A quantitative histochemical study of the spatial distribution of intrafascicular fiber types in porcine masseter and soleus muscles. Arch Oral Biol. 1994;39:295–300
  15. Lopez-Rivero JL, Diz AM, Monterde JG, Aguera E. Intramuscular distribution of fiber types in the gluteus medius of the horse: a histochemical analysis. Anat Histol Embryol. 1993;22:233–240
  16. Serrano AL, Petrie JL, Rivero JL, Hermanson JW. Myosin isoforms and muscle fiber characteristics in equine gluteus medius muscle. Anat Rec. 1996;244:444–451
  17. Rivero JL, Galisteo AM, Aguera E, Miro F. Skeletal muscle histochemistry in male and female Andalusian and Arabian horses of different ages. Res Vet Sci. 1993;54:160–169
  18. Roneus M. Muscle characteristics in Standardbreds of different ages and sexes. Equine Vet J. 1993;25:143–146
  19. Roneus M, Lindholm A, Asheim A. Muscle characteristics in Thoroughbreds of different ages and sexes. Equine Vet J. 1991;23:207–210
  20. Dingboom EG, Dijkstra G, Enzerink E, van Oudheusden HC, Weijs WA. Postnatal muscle fiber composition of the gluteus medius muscle of Dutch Warmblood foals; maturation and the influence of exercise. Equine Vet J (Suppl). 1999;31:95–100
  21. Dingboom EG, van Oudheusden H, Eizema K, Weijs WA. Changes in fiber type composition of gluteus medius and semitendinosus muscles of Dutch Warmblood foals and the effect of exercise during the first year postpartum. Equine Vet J. 2002;34:177–183
  22. Yamano S, Eto D, Kasashima Y, Hiraga A, Sugiura T, Miyata H. Evaluation of developmental changes in the coexpression of myosin heavy chains and metabolic properties of equine skeletal muscle fibers. Am J Vet Res. 2005;66:401–405
  23. Pehme A, Alev K, Kaasik P, Seene T. Age-related changes in skeletal muscle myosin heavy-chain composition: effect of mechanical loading. J Aging Phys Act. 2004;11:29–44
  24. Welle S, Bhatt K, Thornton CA. High-abundance mRNAs in human muscle: comparison between young and old. J Appl Physiol. 2000;89:297–304
  25. Kim JS, Hinchcliff KW, Yamaguchi M, Beard LA, Markert CD, Devor ST. Age-related changes in metabolic properties of equine skeletal muscle associated with muscle plasticity. Vet J. 2005;169:397–403
  26. Lehnhard RA, McKeever KH, Kearns CF, Beekley MD. Myosin heavy chain profiles and body composition are different in old versus young Standardbred mares. Vet J. 2004;167:59–66
  27. Larsson L. Motor units: remodelling in aged animals. J Gerontol: A Biol Sci. 1995;50A:91–95
  28. Rogers CW, Firth EC, McIlwraith CW, Barneveld A, Goodship AE, Kawcak CE, et al. Evaluation of a new strategy to modulate skeletal development in Thoroughbred performance horses by imposing track-based exercise during growth. Equine Vet J. 2008;40:111–118
  29. Alev K, Seene T. Effect of endurance training on the character of skeletal muscle kinetics. In:  Vain A editors. Acta Academiae Olympiquae Estoniae Tartu. 14:2006;p. 5–17
  30. Booth F, Tseng B, Flück M, Carson J. Molecular and cellular adaptation of muscle in response to physical training. Acta Physiol Scand. 1998;162:343–350
  31. Seene T, Alev K, Kaasik P, Pehme A. Changes in fast-twitch muscle oxidative capacity and myosin isoforms modulation during endurance training. J Sports Med Phys Fitness. 2007;47:124–132
  32. Seene T, Kaasik P, Alev K, Pehme A, Riso EM. Composition and turnover of contractile proteins in volume-overtrained skeletal muscle. Int J Sports Med. 2004;25:438–445
  33. Seene T, Umnova M, Kaasik P, Aru M. The effect of endurance and sprint training on the ultrastructure of extrafusal and intrafusal muscle fibers. In:  Vain A editors. Acta Academiae Olympiquae Estoniae Tartu. 13:2005;p. 16–46
  34. Seene T, Alev K. Effect of muscular activity on the turnover rate of actin and myosin heavy and light chains in different types of skeletal muscle. Int J Sports Med. 1991;12:204–207
  35. Seene T, Kaasik P, Pehme A, Alev K, Riso E-M. The effect of glucocorticoids on the myosin heavy chain isoforms' turnover in skeletal muscle. J Steroid Biochem Mol Biol. 2003;86:201–206
  36. Lehmann M, Foster C, Keul J. Overtraining in endurance athletes: a brief review. Med Sci Sports Exerc. 1993;25:854–862
  37. Lehmann MJ, Lormes W, Opitz-Gress A, Steinacker JM, Netzer N, Foster C, et al. Training and overtraining: an overview and experimental results in endurance sports. J Sports Med Phys Fitness. 1997;37:7–17
  38. Hooper SL, Mackinnon LT, Howard A, Gordon RD, Bachmann AW. Markers for monitoring overtraining and recovery. Med Sci Sports Exerc. 1995;27:106–112
  39. Lambert M, Gibson A, Derman W, Noakes T. Regeneration after ultra-endurance exercise. In:  Lehmann M,  Foster C,  Gastmann U,  Keizer H,  Steinacker J editor. Overload, performance incompetence and regeneration in sport. New York: Kluwer Academic/Plenum Publishers; 1999;p. 163–172
  40. Seene T, Umnova M, Kaasik P. The exercise myopathy. In:  Lehmann M,  Foster C,  Gastmann U,  Keizer H,  Steinacker J editor. Overload, performance incompetence and regeneration in sport. New York: Kluwer Academic/Plenum Publishers; 1999;p. 119–130
  41. Puhke R, Aunola S, Ailanto P, Alev K, Venojärvi M, Rusko H, et al. Adaptive changes of myosin isoforms in response to long-term strength and power training in middle-aged men. J Sports Sci Med. 2006;5:349–358
  42. Campos GER, Luecke TJ, Wendeln HK, Toma K, Hagerman FC, Murray TF, et al. Muscular adaptation in response to three different resistance-training regimens: specificity of repetition maximum training zones. Eur J Appl Physiol. 2002;88:50–60
  43. Williamson DL, Gallagher PM, Carrol CC, Raue U, Trappe SW. Reduction in hybrid single muscle fiber proportions with resistance training in humans. J Appl Physiol. 2001;91:1955–1961
  44. Andersen JL, Gruschy-Knudsen T, Sandri C, Larsson L, Schiaffino S. Bed rest increases the amount of mismatched fibers in human skeletal muscles. J Appl Physiol. 1999;86:455–460
  45. Sharman M, Newton R, Triplett-McBride T, McGuigan M, McBride J, Häkkinen A, et al. Changes in myosin heavy chain composition with heavy resistance training in 60-to 75-year-old men and women. Eur J Appl Physiol. 2001;84:127–132
  46. Talmadge R, Castro M, Apple D, Dudley G. Phenotypic adaptations in human muscle fibers 6 and 24 wk after spinal cord injury. J Appl Physiol. 2002;92:147–154
  47. Harber MP, Gallagher PM, Trautmann J, Trappe SW. Myosin heavy chain composition of single muscle fibers in male distance runners. Int J Sports Med. 2002;23:484–488
  48. Andersen JL, Aagaard P. Myosin heavy chain IIX overshoot in human skeletal muscle. Muscle Nerve. 2000;23:1095–1104
  49. Noakes T. Physiological models to understand exercise fatigue and the adaptations that predict or enhance athletic performance. Scand J Med Sci Sports. 2000;10:123–140
  50. Thayer R, Collins E, Noble G, Taylor A. A decrease of aerobic endurance training: Histological evidence for fiber type transformation. J Sports Med Phys Fitness. 2000;40:284–289
  51. Essen-Gustavsson B, McMiken D, Karlstrom K, Lindholm A, Persson S, Thornton J. Muscular adaptation of horses during intensive training and detraining. Equine Vet J. 1989;21:27–33
  52. Gondim FJ, Modolo LV, Campos GE, Salgado I. Neuronal nitric oxide synthase is heterogeneously distributed in equine myofibers and highly expressed in endurance trained horses. Can J Vet Res. 2005;69:46–52
  53. Rivero JL, Henckel P. Muscle biopsy index for discriminating between endurance horses with different performance records. Res Vet Sci. 1996;61:49–54
  54. Rivero JL, Ruz MC, Serrano AL, Diz AM. Effects of a 3 months endurance training programme on skeletal muscle histochemistry in Andalusian, Arabian and Anglo-Arabian horses. Equine Vet J. 1995;27:51–59
  55. Rivero JL, Serrano AL, Henckel P, Aguera E. Muscle fiber type composition and fiber size in successfully and unsuccessfully endurance-raced horses. J Appl Physiol. 1993;75:1758–1766
  56. Lopez-Rivero JL, Morales-Lopez JL, Galisteo AM, Aguera E. Muscle fiber type composition in untrained and endurance-trained Andalusian and Arab horses. Equine Vet J. 1991;23:91–93
  57. Hodgson DR, Rose RJ. Effects of a nine-month endurance training programme on muscle composition in the horse. Vet Rec. 1987;121:271–274
  58. Serrano AL, Quiroz-Rothe E, Lopez-Rivero JL. Early and long-term changes of equine skeletal muscle in response to endurance training and detraining. Pflugers Arch Eur J Physiol. 2000;441:263–274
  59. Lopez-Rivero JL, Aguera E, Monterde JG, Vivo J, Rodriguez-Barbudo MV. Skeletal muscle fiber size in untrained and endurance-trained horses. Am J Vet Res. 1992;53:847–850
  60. Eto D, Yamano S, Kasashima Y, Sugiura T, Nasu T, Tokuriki M, et al. Effect of controlled exercise on middle gluteal muscle fiber composition in Thoroughbred foals. Equine Vet J. 2003;35:676–680
  61. Yamano S, Eto D, Sugiura T, Kai M, Hiraga A, Tokuriki M, et al. Effect of growth and training on muscle adaptation in Thoroughbred horses. Am J Vet Res. 2002;63:1408–1412
  62. Miyata H, Sugiura T, Kai M, Hiraga A, Tokuriki M. Muscle adaptation of Thoroughbred racehorses trained on a flat or sloped track. Am J Vet Res. 1999;60:1536–1539
  63. Rivero JL, Talmadge RJ, Edgerton VR. Correlation between myofibrillar ATPase activity and myosin heavy chain composition in equine skeletal muscle and the influence of training. Anat Rec. 1996;246:195–207
  64. Yamano S, Eto D, Hiraga A, Miyata H. Recruitment pattern of muscle fiber type during high intensity exercise (60-100% VO2max) in Thoroughbred horses. Res Vet Sci. 2006;80:109–115
  65. Roneus N, Essen-Gustavsson B. Skeletal muscle characteristics and metabolic response to exercise in young Standardbreds. Am J Vet Res. 1997;58:167–170
  66. Roneus N, Essen-Gustavsson B, Lindholm A, Eriksson Y. Plasma lactate response to submaximal and maximal exercise tests with training, and its relationship to performance and muscle characteristics in Standardbred trotters. Equine Vet J. 1994;26:117–121
  67. Henckel P. Training and growth induced changes in the middle gluteal muscle of young Standardbred trotters. Equine Vet J. 1983;15:134–140
  68. Roneus M, Essen-Gustavsson B, Lindholm A, Persson SG. Skeletal muscle characteristics in young trained and untrained Standardbred trotters. Equine Vet J. 1992;24:292–294
  69. Gottlieb M, Essen-Gustavsson B, Lindholm A, Persson SG. Effects of a draft-loaded interval-training program on skeletal muscle in the horse. J Appl Physiol. 1989;67:570–577
  70. Rivero JL, Serrano AL. Skeletal myosin heavy chain composition and carriage training. Equine Vet J (Suppl). 1999;30:318–323
  71. Serrano AL, Rivero JL. Myosin heavy chain profile of equine gluteus medius muscle following prolonged draught-exercise training and detraining. J Muscle Res Cell Motil. 2000;21:235–245
  72. Kim JS, Hinchcliff KW, Yamaguchi M, Beard LA, Markert CD, Devor ST. Exercise training increases oxidative capacity and attenuates exercise-induced ultrastructural damage in skeletal muscle of aged horses. J Appl Physiol. 2005;98:334–342
  73. Kendall B, Eston R. Exercise-induced muscle damage and the potential protective role of estrogen. Sports Med. 2002;32:103–123
  74. Kibler W, Chandler T. Musculoskeletal and orthopedic considerations. In:  Kreider R,  Fry A,  O'Toole M editor. Overtraining in sport. Champaign (IL): Human Kinetics; 1998;p. 169–190
  75. Lehmann M, Baur S, Netzer N, Gastmann U. Monitoring high-intensity endurance training using neuromuscular excitability to recognize overtraining. Eur J Appl Physiol Occup Physiol. 1997;76:187–191
  76. Seene T, Umnova M. Relations between changes in the turnover rate of contractile proteins, activation of satellite cells and ultra-structural response of neuromuscular junctions in the fast-oxidative-glycolytic muscle fibers in endurance trained rats. Basic Appl Myol. 1992;2:34–46
  77. Umnova M, Seene T. The effect of increased functional load on the activation of satellite cells in the skeletal muscle of adult rats. Int J Spots Med. 1991;12:501–504
  78. Takekura H, Yoshioka T. Different metabolic responses to exercise training programmes in single rat muscle fibers. J Muscle Res Cell Motil. 1990;11:105–113
  79. Takekura H, Yoshioka T. Specific mitochondrial responses to running training are induced in each type of rat single muscle fibers. Jpn J Physiol. 1989;39:497–509

 Refereed

PII: S0737-0806(08)00190-1

doi: 10.1016/j.jevs.2008.05.007

Journal of Equine Veterinary Science
Volume 28, Issue 7 , Pages 395-401 , July 2008

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