Journal of Equine Veterinary Science
Volume 28, Issue 5 , Pages 315-316 , May 2008

Endocrine Testing in Horses: Metabolic Syndrome and Cushing's Disease

  • Thomas J. Divers, DVM, DACVIM, ACVECC

      Affiliations

    • Corresponding Author InformationReprint requests: Thomas J. Divers, DVM, DACVIM, ACVECC, Professor of Medicine, Cornell University, College of Veterinary Medicine, Department of Clinical Sciences, Ithaca, NY 14853.

References 

  1. Kronfeld DS, Treiber KH, Hess TM, Splan RK, Byrd BM, Staniar WB, et al. Metabolic syndrome in healthy ponies facilitates nutritional countermeasures against pasture laminitis. J Nutr. 2006;136(Suppl 7):2090S–2093S
  2. Treiber KH, Kronfeld DS, Hells TM, Boston RC, Harris PA. Use of proxies and reference quintiles obtained from minimal model analysis for determination of insulin sensitivity and pancreatic beta-cell responsiveness in horses. Am J Vet Res. 2005;66:2114–2221
  3. Eiler H, Frank N, Andrews FM, Oliver JW, Fecteau KA. Physiologic assessment of blood glucose homeostasis via combined intravenous glucose and insulin testing in horses. Am J Vet Res. 2005;66:1598–1604
  4. Pratt SE, Geor RJ, McCutcheon LJ. Repeatability of 2 methods for assessment of insulin sensitivity and glucose dynamics in horses. J Vet Intern Med. 2005;19:883–888
  5. Firshman AM, Valberg SJ. Factors affecting clinical assessment of insulin sensitivity in horses. Equine Vet J. 2007;39:567–575
  6. Cartmill JA, Thompson DL, Storer WA, Gentry LR, Huff NK. Endocrine responses in mares and geldings with high body condition scores grouped by high vs. low resting leptin concentrations. J Anim Sci. 2003;81:2311–2321
  7. Donaldson MT, McDonnell SM, Schanbacher BJ, Lamb SV, McFarlane D, Beech J. Variation in plasma adrenocorticotropic hormone concentration and dexamethasone suppression test results with season, age, and sex in healthy ponies and mares. J Vet Intern Med. 2005;19:217–222
  8. Perkins GA, Lamb S, Erb HN, Schanbacher B, Nydam DV, Divers TJ. Plasma adrenocorticotropin (ACTH) concentrations and clinical response in horses treated for equine Cushing's disease with cyproheptadine or pergolide. Equine Vet J. 2002;34:679–695
  9. Frank N, Andrews FM, Sommardahl CS, Eiler H, Rohrbach BW, Donnell RL. Evaluation of the combined dexamethasone suppression/thyrotropin-releasing hormone stimulation test for detection of pars intermedia pituitary adenomas in horses. J Vet Intern Med. 2006;20:987–993
  10. Beech J, Boston R, Lindborg S, Russell GE. Adrenocorticotropin concentration following administration of thyrotropin-releasing hormone in healthy horses and those with pituitary pars intermedia dysfunction and pituitary gland hyperplasia. J Am Vet Med Assoc. 2007;231:417–426
  11. Miller MA, Pardo ID, Jackson LP, Moore GE, Sojka JE. Correlation of pituitary histomorphometry with adrenocorticotrophic hormone response to domperidone administration in the diagnosis of equine pituitary pars intermedia dysfunction. Vet Pathol. 2008;45:26–38
  12. Messer NT, Johnson PJ. Evidence-based literature pertaining to thyroid dysfunction and Cushing's syndrome in the horse. Vet Clin North Am Equine Pract. 2007;23:329–364

 Refereed

PII: S0737-0806(08)00118-4

doi: 10.1016/j.jevs.2008.04.004

Journal of Equine Veterinary Science
Volume 28, Issue 5 , Pages 315-316 , May 2008