Journal of Equine Veterinary Science
Volume 28, Issue 3 , Pages 176-179 , March 2008

Evidence-Based Treatment for Laminitis—What Works?

  • Rustin M. Moore, DVM, PhD, DACVS

      Affiliations

    • Corresponding Author InformationReprint requests: Rustin M. Moore, DVM, PhD, DACVS, From the Department of Veterinary Clinical Science, College of Veterinary Medicine, The Ohio State University, Columbus, OH.

References 

  1. Cook JL. Outcomes-based patient care in veterinary surgery: What is an outcome measure?. Vet Surg. 2007;36(3):187–189
  2. Pollitt CC, van Eps AW. Prolonged, continuous distal limb cryotherapy in the horse. Equine Vet J. 2004;36:216–220
  3. Worster AA, Gaughan EM, Hoskinson JJ, Sargeant J, Erb JH. Effects of external thermal manipulation on laminar temperature and perfusion scintigraphy of the equine digit. N Z Vet J. 2000;48:111–116
  4. van Eps AW, Pollitt CC. Equine laminitis: cryotherapy reduces the severity of the acute lesion. Equine Vet J. 2004;36:255–260
  5. Slater MR, Hood DM, Carter GK. Descriptive epidemiological study of equine lamin. Equine Vet J. 1995;27:364–367
  6. Medical treatment of acute laminitis: Questionnaire results. Equine Laminitis Research Meeting and Panel. Louisville, KY 2004, pp 6.
  7. Ingle-Fehr JE, Baxter GM. The effect of oral isoxsuprine and pentoxyfylline on digit and laminar blood flow in healthy horses. Vet Surg. 1999;28(3):154–160
  8. Hunt RJ, Brandon CI, McCann ME. Effects of acetylpromazine, xylazine and vertical load on digital arterial blood flow in horses. Am J Vet Res. 1994;55(3):375–378
  9. Leise BS, Fugler LA, Stokes AM, Eades SC, Moore RM. Effects of intramuscular administration of acepromazine on palmar digital blood flow, palmar digital arterial pressure, transverse facial arterial pressure, and packed cell volume in clinically healthy, conscious horses. Vet Surg. 2007;36(8):717–723
  10. Walker M, Geiser D. Effects of acetylpromazine on the hemodynamics of the equine matatarsal artely, as determined by two dimensional real-time and pulsed Doppler ultrasonography. Am J Vet Res. 1986;47(5):1075–1078
  11. Hinckley KA, Fearn S, Howard BR, Henderson IW. Nitric oxide donors as treatment for grass induced acute laminitis in ponies. Equine Vet J. 1996;28:17–28
  12. Gilhooly M, Eades SC, Stokes AM, Moore RM. Effects of topical nitroglycerine patches and nitroglycerine ointment on digital venous plasma nitric oxide concentrations and digital blood flow in healthy conscious horses. Vet Surg. 2005;34:604–609
  13. Blikslager AT, Yin C, Cochran AM, Wooten JG, Pettigrew A, Belknap JK. Cyclooxygenase expression in the early stages of equine laminitis: a cytologic study. J Vet Intern Med. 2006;20:1191–1196
  14. Fontaine GL, Belknap JK, Allen D, Moore JN, Kroll DL. Expression of interleukin-1b in the digital lamellae of horses in the prodromal stage of experimentally induced laminitis. Am J Vet Res. 2001;62:714–720
  15. Waguespack RW, Cochran A, Belknap JK. Expression of the cyclooxygenase isoforms in the prodromal stage of black walnut-induced laminitis in horses. Am J Vet Res. 2004;65:1724–1729
  16. Pass MA, Pollitt S, Pollitt CC. Decreased glucose metabolism causes separation of lamellae in vitro. A trigger for laminitis? Equine Vet J. 1998;26:133–138
  17. French KR, Pollitt CC. Equine laminitis: Glucose deprivation and MMP activation induce dermo-epidermal separation in vitro. Equine Vet J. 2004;36(3):261–266
  18. Treiber KH, Kronfeld DS, Geor RJ. Insulin resistance in equids: possible role in laminitis. J Nutr. 2006;136(7 Suppl):2094S–2098S

 Refereed

PII: S0737-0806(08)00023-3

doi: 10.1016/j.jevs.2008.01.015

Journal of Equine Veterinary Science
Volume 28, Issue 3 , Pages 176-179 , March 2008

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