Journal of Equine Veterinary Science
Volume 27, Issue 5 , Pages 221-227 , May 2007

Hyperthermia and Delayed-Onset Myopathy after Recovery from Anesthesia in a Horse

  • Nicola Grint, BVSc, DVA, DiplECVA, MRCVS

      Affiliations

    • From the Division of Veterinary Anaesthesia
    • Corresponding Author InformationReprint requests to: Nicola Grint, BVSc, DVA, DiplECVA, MRCVS, Division of Veterinary Anaesthesia, Philip Leverhulme Equine Hospital, University of Liverpool, Leahurst, Neston, Wirral CH43 5SX, United Kingdom.
  • ,
  • Dylan Gorvy, BSc, BVSc, PhD, CertES (Soft Tissue), MRCVS

      Affiliations

    • Division of Equine Studies, Philip Leverhulme Equine Hospital, University of Liverpool, Leahurst, Neston, Wirral, United Kingdom
  • ,
  • Alexandra Dugdale, MA, VetMB, DVA, DiplECVA, MRCVS

      Affiliations

    • From the Division of Veterinary Anaesthesia

References 

  1. Wyn-Jones G. The diagnosis of the causes of lameness. In:  Wyn-Jones G editors. Equine lameness. Oxford: Blackwell Scientific Publications; 1985;p. 5
  2. Manley SV, Kelly AB, Hodgson D. Malignant hyperthermia-like reactions in three anesthetized horses. J Am Vet Med Assoc. 1983;183:85–89
  3. Waldron-Mease E, Klein LV, Rosenberg H, Leitch M. Malignant hyperthermia in a halothane-anesthetized horse. J Am Vet Med Assoc. 1981;179:896–898
  4. Klein L, Ailes N, Fackelman GE, Kellon E, Rosenberg H. Postanaesthetic equine myopathy suggestive of malignant hyperthermia; a case report. Vet Surg. 1989;18:479–482
  5. Brunson DB, Hogan KJ. Malignant hyperthermia; a syndrome not a disease. Vet Clin North Am: Small Anim Pract. 2004;34:1419–1433
  6. Henschel EO. Alarm sheet. In:  Henschel EL editors. Malignant hyperthermia: current concepts. Appleton-Century-Crofts; 1977;inside cover
  7. Van Den Hende C, Lister D, Muyelle E, Ooms L, Oyaert W. Malignant hyperthermia in Belgian Landrace pigs rested or exercised before exposure to halothane. Br J Anaesth. 1976;48:821–829
  8. Klein L. Anesthetic complications in the horse. Vet Clin North Am Equine Pract. 1990;6:665–692
  9. McGrath CJ, Rempel WE, Addis PB. Acepromazine and droperidol inhibition of halothane-induced malignant hyperthermia (porcine stress syndrome) in swine. Am J Vet Res. 1981;42:195–202
  10. Delay J, Deniker P. Drug-induced extrapyramidal syndromes. In:  Vinken PJ,  Bruyn GW editor. Handbook of clinical neurology: diseases of the basal ganglia. Elsevier North-Holland; 1968;p. 248–266
  11. Greene S. Hepatic disease. In:  Thurmon JC,  Tranquilli WJ,  Benson GJ editor. Lumb & Jones' veterinary anaesthesia. Philadelphia: Lippincott Williams & Wilkins; 1996;p. 791–798
  12. Taylor PM, Clarke KW. Intravenous anaesthesia. In: Handbook of equine anaesthesia. Philadelphia: WB Saunders; 1999;p. 33–54
  13. http://www.nwlabs.co.uk. Accessed March 2007.
  14. Smith RKW, Dyson SJ, Head MJ, Butson RJ. Ultrasonography of the equine triceps muscle before and after general anaesthesia and in post anaesthetic myopathy. Equine Vet J. 1996;28:311–319
  15. Kalpravidh S, Lumb WV, Wright M, Heath RB. Effects of butorphanol, flunixin, levorphanol, morphine and xylazine in ponies. Am J Vet Res. 1984;45:217–223
  16. Foreman JH. The exhausted horse syndrome. Vet Clin North Am Equine Pract. 1998;14:205–219
  17. Khan A, Jaffe JH, Nelson WH, Morrison B. Resolution of neurolept malignant syndrome with dantrolene sodium; case report. J Clin Psych. 1985;46:244–246
  18. Court MH, Engelking LR, Dodman NH. Pharmacokinetics of dantrolene sodium in horses. J Vet Pharm Ther. 1987;10:218–226
  19. Nielsen L. Chemical immobilization of free-ranging terrestrial mammals. In:  Thurmon JC,  Tranquilli WJ,  Benson GJ editor. Lumb & Jones' veterinary anaesthesia. Philadelphia: Lippincott Williams & Wilkins; 1996;p. 736–766
  20. Marlin DJ, Scott CM, Roberts CA, Casas I, Holah G, Schroter RC. Post anaesthetic changes in compartmental body temperature accompanying intermittent cold water cooling in the hyperthermic horse. Equine Vet J. 1998;30:28–34
  21. Hall LW, Clarke KW, Trim C. Prevention and management of anaesthetic accidents and crises. In:  Hall LW,  Clarke KW,  Trim C editor. Veterinary anaesthesia. Philadelphia: WB Saunders; 2001;p. 507–533
  22. Martin L. Pitfalls in blood gas interpretation. In:  Martin L editors. All you really need to know to interpret arterial blood gases. Philadelphia: Lippincott, Williams & Wilkins; 1999;p. 218–223
  23. Connolly DA, Sayers SP, McHugh MP. Treatment and prevention of delayed onset muscle soreness. J Strength Cond Res. 2003;17:197–208
  24. Watanabe M, Ireda S, Kameya T. Evaluation of myoglobin determination for the diagnosis of tying up syndrome in racehorses in Japan. Exp Rep Equine Health Lab. 1978;15:79
  25. MacLeay JM. Diseases of the musculoskeletal system. In:  Reed SM,  Bayly WM,  Sellon DC editor. Equine internal medicine. Philadelphia: WB Saunders; 2004;p. 461–531
  26. Raisis AL, Young LE, Blissitt KJ, Brearley JC, Meire HB, Taylor PM, et al. A comparison of the haemodynamic effects of isoflurane and halothane anaesthesia in horses. Equine Vet J. 2000;32:318–326
  27. Ledwith A, McGowan CM. Muscle biopsy: a routine diagnostic procedure. Equine Vet Ed. 2004;16:62–67
  28. Knottenbelt DC. Vital signs, normal values. In:  Knottenbelt DC editors. Equine formulary. Philadelphia: Saunders Elsevier; 2006;p. 3–37

 Refereed

PII: S0737-0806(07)00150-5

doi: 10.1016/j.jevs.2007.04.006

Journal of Equine Veterinary Science
Volume 27, Issue 5 , Pages 221-227 , May 2007