Journal of Equine Veterinary Science
Volume 27, Issue 2 , Pages 58-61 , February 2007

Comparison of Compounded Deslorelin and hCG for Induction of Ovulation in Mares

  • P.M. McCue, DVM, PhD

      Affiliations

    • Corresponding Author InformationReprint requests to: P.M. McCue, 3194 Rampart Road, Ft. Collins, CO 80523.
    • ,
  • C. Magee, DVM
    • ,
  • E.K. Gee, BVSc, PhD

References 

  1. Chavatte P, Palmer E. Induction of ovulation in the mare. Equine Vet Educ. 1998;10:26–30
  2. Palmer E. Induction of ovulation. In:  McKinnon AO,  Voss JL editor. Equine reproduction. Baltimore: Williams and Wilkins; 1993;p. 344–347
  3. McCue PM. Induction of ovulation. In:  Robinson NE editors. Current therapy in equine medicine. 5th ed.. Philadelphia: Saunders; 2003;p. 240–242
  4. Meinert C, Silva JFS, Kroetz I, Klug E, Trigg TE, Hoppen HO, et al. Advancing the time of ovulation in the mare with a short-term implant releasing the GnRH analogue deslorelin. Equine Vet J. 1993;25:65–68
  5. Roser JF, Boime I, Colgin M, Niswender KD. Development and efficacy of recombinant eLH and eFSH. In: Proceedings West Coast Equine Reproduction Symposium II; 2005:39–52.
  6. Voss JL. Human chorionic gonadotropin. In:  McKinnon AO,  Voss JL editor. Equine reproduction. Baltimore: Williams and Wilkins; 1993;p. 325–328
  7. Evans JW, Roser JF, Mikuckis GM. Comparison of the interaction of equine LH and human chorionic gonadotropin to equine testicular receptors. J Reprod Fertil. 1982;32(suppl.):113–121
  8. Mumford EL, Squires EL, Jöchle W, Harrison LA, Nett TM, Trigg TE. Use of deslorelin short-term implants to induce ovulation in cycling mares during three consecutive estrous cycles. Anim Reprod Sci. 1995;39:129–140
  9. Pycock JF. Use of ultrasound to stage estrus and predict ovulation. In:  Robinson NE editors. Current therapy in equine medicine. 5th ed.. Philadelphia: Saunders; 2003;p. 242–245
  10. Meyers PJ, Jöchle W, Trigg TE. Acceleration of ovulation in the mare with the use of the GnRH analog, deslorelin acetate. In: Proceedings 40th Annual Convention of the American Association of Equine Practitioners; 1994:13–14.
  11. Morehead J, Blanchard T. Clinical experience with deslorelin (Ovuplant™) in a Kentucky Thoroughbred broodmare practice. J Equine Vet Sci. 1999;20:358–402
  12. Vanderwall DK, Juergens TD, Woods GL. Reproductive performance of commercial broodmares after induction of ovulation with hCG or Ovuplant™ (deslorelin). J Equine Vet Sci. 2001;21:539–542
  13. Farquhar VJ, McCue PM, Carnevale EM, Squires EL. Interovulatory intervals of embryo donor mares administered deslorelin acetate to induce ovulation. Theriogenology. 2001;55:362
  14. Farquhar VJ, McCue PM, Nett TM, Squires EL. Effect of deslorelin acetate on gonadotropin secretion and ovarian follicle development in cycling mares. J Am Vet Med Assoc. 2001;218:749–752
  15. Johnson CA, Thompson DL, Cartmill JA. Pituitary responsiveness to GnRH in mares following deslorelin acetate implantation to hasten ovulation. J Anim Sci. 2002;80:2681–2687
  16. Johnson CA, Thompson DL, Kulinski KM, Guitreau AM. Prolonged interovulatory interval and hormonal changes in mares following the use of Ovuplant™ to hasten ovulation. J Equine Vet Sci. 2000;20:331–336
  17. Farquhar VJ, McCue PM, Carnevale EM, Nett TM, Squires EL. Deslorelin acetate (Ovuplant) therapy in cycling mares: effect of implant removal on FSH secretion and ovarian function. Equine Vet J. 2002;34:417–420
  18. McCue PM, Farquhar VJ, Carnevale EM, Squires EL. Removal of deslorelin (Ovuplant™) implant 48 h after administration results in normal interovulatory intervals in mares. Theriogenology. 2002;58:865–870
  19. Farquhar VJ, McCue PM, Vanderwall DK, Squires EL. Efficacy of the GnRH agonist deslorelin acetate for inducing ovulation in mares relative to age of mare and season. J Equine Vet Sci. 2000;20:8–11
  20. Sullivan JJ, Parker WG, Larson LL. Duration of estrus and ovulation time in nonlactating mares given human chorionic gonadotropin during three successive estrous periods. J Am Vet Med Assoc. 1973;162:895–898
  21. McCue PM, Hudson JJ, Bruemmer JE, Squires EL. Efficacy of hCG at inducing ovulation: a new look at an old issue. In: Proceedings 50th Annual Convention of the American Association of Equine Practitioners; 2004:510–513.
  22. Wilson CG, Downie CR, Hughes JP, Roser JF. Effects of repeated hCG injections on reproductive efficiency in mares. J Equine Vet Sci. 1990;10:301–308
  23. Roser JF, Kiefer BL, Evans JW, Neely DP, Pacheco CA. The development of antibodies to human chorionic gonadotrophin following its repeated injection in the cyclic mare. J Reprod Fert (Suppl). 1979;27:173–179
  24. Barbacini S, Zavaglia G, Gulden P, Marchi V, Necchi D. Retrospective study on the efficacy of hCG in an equine artificial insemination programme using frozen semen. Equine Vet Educ. 2000;12:312–332
  25. Loy RG, Hughes JP. The effects of human chorionic gonadotropin on ovulation, length of estrus, and fertility in the mare. Cornell Vet. 1966;56:41–50

 Refereed

PII: S0737-0806(06)00698-8

doi: 10.1016/j.jevs.2006.12.003

Journal of Equine Veterinary Science
Volume 27, Issue 2 , Pages 58-61 , February 2007

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