Journal of Equine Veterinary Science
Volume 26, Issue 2 , Pages 59-66 , February 2006

Transendoscopic injection of poly-L-lactic acid into the soft palate in horses: A new therapy for dorsal displacement of the soft palate?

  • Anja Cehak, Dr Med Vet

      Affiliations

    • Corresponding Author InformationReprint requests: Dr. Anja Cehak, Equine Clinic, Bischofsholer Damm 15, 30173 Hannover, Germany
    • Equine Clinic, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany
    • ,
  • Eckehard Deegen, Prof Dr Dr Med Vet

      Affiliations

    • Equine Clinic, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany
    • ,
  • Wolfgang Drommer, Prof Dr Dr Med Vet

      Affiliations

    • Department of Pathology, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany
    • ,
  • Elke Lütkefels, Dr Med Vet

      Affiliations

    • Department of Pathology, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany
    • ,
  • Bernhard Ohnesorge, PD Dr Med Vet Dipl ECEIM

      Affiliations

    • Equine Clinic, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173 Hannover, Germany

References 

  1. Haynes PF . Dorsal displacement of the soft palate and epiglottic entrapment: diagnosis, management and interrelationships . Compend Contin Educ Pract Vet . 1983;5:379–389
  2. Holcombe SJ , Derksen FJ , Stick JA , et al.   Effect of bilateral tenectomy of the tensor veli palatini muscle on soft palate function in horses . Am J Vet Res . 1997;58:317–321
  3. Franklin SH , Naylor JRJ , Lane JG . Effect of dorsal displacement of the soft palate on ventilation and airflow during high-intensity exercise . Equine Vet J . 2002;34(Suppl):379–384
  4. Franklin SH . Pathogenesis of dorsal displacement of the soft palate . In: Proc 42nd BEVA Congress . 2003;131–133
  5. Durcharme NG , Hackett RP , Woodie JB , et al.   Investigations into the role of the thyroid muscles in the pathogenesis of dorsal displacement of the soft palate in horses . Equine Vet J . 2003;35:258–263
  6. Haynes PF . Persistent dorsal displacement of the soft palate associated with epiglottic shortening in two horses . JAVMA . 1981;179:677–681
  7. Durcharme NG, Holcombe SJ. The function of the extrinsic and intrinsic musculature in stabilizing the upper airways. In: Proc World Equine Airway Symposium, Edinburgh 2001.
  8. Anderson JD , Tulleners EP , Johnston JK , et al.   Sternothyrohyoideus myectomy or staphylectomy for treatment of intermittent dorsal displacement of the soft palate in racehorses: 209 cases (1986-1991) . JAVMA . 1995;206:1909–1912
  9. Tate PL , Sweeney CL , Bowmann KF , et al.   Transendoscopic Nd:YAG laser surgery for treatment of epiglottic entrapment and dorsal displacement of the soft palate in the horse . Vet Surg . 1990;19:356–363
  10. Hogan PM , Palmer SE , Congelosi M . Transendoscopic laser cauterization of the soft palate as an adjunctive treatment for dorsal displacement in the racehorse . Proc Am Assoc Equine Pract . 2002;48:228–230
  11. Smith JJ , Embertson RM . Sternothyroideus myotomy, staphylectomy, and oral caudal photothermoplasty for treatment of dorsal displacement of the soft palate in 102 thoroughbred racehorses . Vet Surg . 2005;34:5–10
  12. Ohnesorge B, Deegen E. Transendoskopische Laserchirurgie der belastungsinduzierten Dorsalverlagerung des Gaumensegels. In Proceedings. Dtsch Vet Med Gesellsch eds. 15. Jahrestagung der Fachgruppe “Pferdekrankheiten.” Wiesbaden: DVG-Selbstverlag. 1998;190-9
  13. Hackett RP , Ducharme NG . Soft palate displacement-pathophysiology and treatment . In: Proc 21st Ann Forum Am Coll Vet Surg . 1993;179–181
  14. Jaeger-Hauer K , Luetkefels E , Ohnesorge B , et al.   Experimentelle Untersuchung zur Wirkung einer laserchirurgischen Therapie bei Gaumensegelverlagerung des Pferdes . Tieraerztl Praxis . 2003;31(G):18–24
  15. O'Rielly JL , Beard WL , Renn TN , et al.   Effect of combined staphylectomy and laryngotomy on upper airway mechanics in clinically normal horses . Am J Vet Res . 1997;58:1018–1021
  16. Durcharme NG . Management options for DDSP . In: Proc 42nd BEVA Congress . 2003;134–136
  17. Linford RL , O'Brien TR , Wheat JD , et al.   Radiographic assessment of epiglottic length and pharyngeal and laryngeal diameters in the Thoroughbred . Am J Vet Res . 1983;44:1660–1666
  18. Raphel CF . Endoscopic findings in the upper respiratory tract of 479 horses . JAVMA . 1982;5:470–473
  19. Kronenthal RL . Biodegradable polymers in medicine and surgery . Polymer Sci Tech . 1975;8:120–137
  20. Rokkanen P , Bostman O , Vainionpa S , et al.   Absorbable devices in the fixation of fractures . J Trauma, Suppl . 1996;40(Suppl):5123–5127
  21. Tsakala M , Gillet J , Gillard J . New antimalarial sustained-release formulations based on bioresorbable polymers: therapeutic evaluation using plasmodium berghei model . J Pharm Belg . 1990;45:5–11
  22. Baudler A , Luetkefels E , Drommer W , et al.   Experimental studies on epiglottic hypoplasia in horses: transendoscopic injection of collagen and polytetrafluoroethylene . Dtsch Tieraerztl Wschr . 2003;110:160–165
  23. Pistner H , Gutwald R , Ordnung R , et al.   Poly(L-lactide): a long-term degradation study in vivo, I Biological results . Biomaterials . 1993;14:671–677
  24. Ohnesorge B , Von Oppen T , Cehak A . Transendoscopic implant injection therapy of soft palate and laryngeal diseases in horses—Part 1: Epiglottic hypoplasia and small cleft soft palate . Pferdeheilkunde . 2002;6:513–520
  25. Streit M , Brand CU , Braathen LR . Soft tissue augmentation for treatment of wrinkles and scars of the face . Tier Umsch . 1999;56:212–218
  26. Lowe NJ, Maxwell CA, Lowe P, et al. Hyaluronic acid skin fillers: adverse reactions and skin testing. J Am Acad Dermatol 200; 145:930-3.
  27. Keffe J , Wauk L , Chu S , et al.   Clinical use of injectable bovine collagen: a decade of experience . Clin Mat . 1992;9:155–162

 RefereedSupported by European Aesthetics, Ismaning, Germany.

PII: S0737-0806(05)00606-4

doi: 10.1016/j.jevs.2005.12.004

Journal of Equine Veterinary Science
Volume 26, Issue 2 , Pages 59-66 , February 2006

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