Journal of Equine Veterinary Science
Volume 23, Issue 7 , Pages 295-300 , July 2003

Efficacy of Intramuscular Chondroitin Sulfate and Compounded Acetyl-d-Glucosamine in a Positive Controlled Study of Equine Carpitis

  • Gary W White, DVM

      Affiliations

    • Sallisaw Equine Clinic, Sallisaw, Oklahoma, USA
    • Corresponding Author InformationReprint requests: Gary W. White, DVM, GCT Consulting Services, Inc, PO Box 733, Sallisaw, OK 74955
    • ,
  • Trent Stites, DVM

      Affiliations

    • Sallisaw Equine Clinic, Sallisaw, Oklahoma, USA
    • ,
  • E.Wynn Jones, FRCVS, PhD

      Affiliations

    • Sallisaw Equine Clinic, Sallisaw, Oklahoma, USA
    • ,
  • Scott Jordan, PhD

      Affiliations

    • Arkansas Tech University, Russellville, Arkansas, USA

References 

    References
  1. McIlwraith CW. Diseases of joints, tendons, ligaments, and related structures. In:  Stashak TS editors. Adams' lameness in horses. 5th ed.. Baltimore (MD): Lippincott, Williams, & Wilkins; 2002;
  2. McIlwraith CW, Frisbie DD, Kawchek CE. Current treatments for traumatic synovitis, capsulitis, and osteoarthritis. Proc Am Assoc Equine Pract. 2001;47:180–206
  3. Hanson R. Oral glycosaminoglycans in treatment of degenerative joint diseases in horses. Equine Pract. 1996;18:18–22
  4. White GW, Jones EW, Hamm J, et al.  The efficacy of orally administered sulfated glycosaminoglycans in chemically induced equine synovitis and degenerative joint disease. J Equine Vet Sci. 1994;14:350–353
  5. Clayton HM, Almeida PE, Prades M, et al.  Double-blind study of the effects of an oral supplement intended to support joint health in horses with tarsal degenerative joint disease. Proc Am Assoc Equine Pract. 2002;48:314–317
  6. White GW, Sanders T, Stites T, et al.  Efficacy of systemically administered antiarthritic drugs in an induced equine carpitis model. Proc Am Assoc Equine Pract. 1996;42:135–138
  7. Freedom of Information Summary NADA 140–901, Adequan im, Luitpold Pharmaceuticals, Inc; Shirley, NY 11967.
  8. McIlwraith CW. Disease processes of synovial membrane, fibrous capsule, ligaments, and articular cartilage. Proc Am Assoc Equine Pract. 2001;47:142–156
  9. Cornelissen BPM, Rijkehnuizen ABM, van den Hoogen BM, et al.  Experimental model of synovitis/capsulitis in the equine metacarpaophalangeal joint. Am J Vet Res. 1998;59:978–985
  10. Palmer JL, Bertone AL. Experimentally-induced synovitis as a model for acute synovitis in the horse. Equine Vet J. 1994;26:492–495
  11. Data on file at Luitpold Pharmaceuticals, Inc; Shirley, NY.
  12. Bertone JJ. Drug quality and antimicrobial use. Proc Am Assoc Equine Pract. 2001;47:103–104
  13. Caron JP, Genovese RL. Principals and practices of joint disease treatment. In:  Ross MW,  Dyson SJ editor. Diagnosis and management of lameness in the horse. St Louis (MO): Saunders; 2003;
  14. Byron CR, Orth MW, Venta PJ, et al.  Influence of glucosamine on matrix metalloprotease expression and activity in lipopolysaccharide-stimulated equine chondrocytes. Am J Vet Res. 2003;64:666–671

☆ This study was supported by a grant from Luitpold Pharmaceuticals, Inc.

PII: S0737-0806(03)01006-2

doi: 10.1016/S0737-0806(03)01006-2

Journal of Equine Veterinary Science
Volume 23, Issue 7 , Pages 295-300 , July 2003

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